Since its creation within UNESCO a half-century ago, the Intergovernmental Oceanographic Commission (IOC) has been at the vanguard of ocean observation, serving to promote international cooperation, coordinate ocean research, and facilitate capacity development. Beginning with the International Indian Ocean Expedition in the early 1960s, and through meaningful partnerships with the Scientific Committee of Ocean Research (SCOR), the International Geosphere-Biosphere Program (IGBP), the Partnership for Observation of the Global Ocean (POGO), and related organizations, IOC has provided invaluable leadership needed to help justify and promote large-scale ocean observation programs. A recent international meeting, co-sponsored by IOC, OceanObs'09: Ocean Information for Society – Sustaining the Benefits, Realizing the Potentials, was held in Venice, Italy, in September 2009. The conference was attended by more than 600 participants from 36 nations to present and discuss ongoing and planned global ocean observation activities. These field efforts represented a diverse spectrum of time-series programs, including the use of satellite remote sensing, moored buoys, autonomous gliders, repeat hydrographic surveys, volunteer ships of opportunity, profiling floats, cabled seafloor observatories, and ship-supported time-series programs, to name a few examples. Each observation program is designed to address a specific set of scientific goals, and each has its own set of challenges to sustain and optimize data return. This article focuses on ecosystem-based, time-series programs that presently rely on ships to make observations, collect samples, and conduct experiments. These ecosystem investigations are an important subset of the much larger portfolio of research-based, ocean time-series programs that derive, in large part, from sustained IOC leadership (Valdés et al., 2010).

Karl, D.M. 2010. Oceanic ecosystem time-series programs: Ten lessons learned. Oceanography 23(3):104–125, https://doi.org/10.5670/oceanog.2010.27.

Aiken, J., J. Fishwick, G. Moore, and K. Pemberton. 2004. The annual cycle of phytoplankton photosynthetic quantum efficiency, pigment composition and optical properties in the western English Channel. Journal of the Marine Biological Association of the UK 84:301–313. [CrossRef]
1. Allen, E.J., and H.W. Harvey. 1928. The laboratory of the Marine Biological Association at Plymouth. Journal of the Marine Biological Association of the UK 15:735–752. [CrossRef]
2. Armstrong, F.A.J., and S. Tibbitts. 1968. Photochemical combustion of organic matter in sea water for nitrogen, phosphorus and carbon determination. Journal of the Marine Biological Association of the UK 48:143–152. [CrossRef]
3. Atkins, W.R.G. 1922a. The hydrogen ion concentration of sea water in its biological relations. Journal of the Marine Biological Association of the UK 12:717–771. [CrossRef]
4. Atkins, W.R.G. 1922b. The hydrogen ion concentration of sea water in its relation to photosynthetic changes. Journal of the Marine Biological Association of the UK 12:93–118. [CrossRef]
5. Atkins, W.R.G. 1923. Note on the oxidisable organic matter of sea water. Journal of the Marine Biological Association of the UK 13:160–163. [CrossRef]
6. Atkins, W.R.G. 1924a. On the thermal stratification of sea water and its importance for the algal plankton. Journal of the Marine Biological Association of the UK 13:693–699. [CrossRef]
7. Atkins, W.R.G. 1924b. On the vertical mixing of sea-water and its importance for the algal plankton. Journal of the Marine Biological Association of the UK 13:319–324. [CrossRef]
8. Atkins, W.R.G. 1926a. A quantitative consideration of some factors concerned in plant growth in water Part I. Some physical factors. Journal du Conseil, Conseil permanent international pour l’exploration de la mer 1:99–126.
9. Atkins, W.R.G. 1926b. A quantitative consideration of some factors concerned in plant growth in water. Part II: Some chemical factors. Journal du Conseil, Conseil permanent international pour l’exploration de la mer 1:197–226.
10. Atkins, W.R.G. 1926c. Phosphate content of sea water in relation to algal plankton. Journal of the Marine Biological Association of the UK 14:447. [CrossRef]
11. Atkins, W.R.G. 1930. Seasonal variations in the phosphate and silicate content of sea-water in relation to the phytoplankton crop. Part V: November 1927 to April 1929, compared with earlier years from 1923. Journal of the Marine Biological Association of the UK 16:821–852. [CrossRef]
12. Bidigare, R.R., F. Chai, M.R. Landry, R. Lukas, C.C.S. Hannides, S.C. Christensen, D.M. Karl, L. Shi, and Y. Chao. 2009. Subtropical ocean ecosystem structure changes forced by North Pacific climate variations. Journal of Plankton Research 31:1,131–1,139.
13. Biggs, R., S.R. Carpenter, and W.A. Brock. 2009. Turning back from the brink: Detecting an impending regime shift in time to avert it. Proceedings of the National Academy of Sciences of the United States of America 106:826–831. [CrossRef]
14. Bond, N.A., J.E. Overland, M. Spillane, and P. Stabeno. 2003. Recent shifts in the state of the North Pacific. Geophysical Research Letters 30(23), 2183. [CrossRef]
15. Brewer, P.G., K.W. Bruland, R.W. Eppley, and J.J. McCarthy. 1986. The Global Ocean Flux Study (GOFS): Status of the U.S.GOFS program. Eos, Transactions, American Geophysical Union 67:827–832.
16. Butler, E.I., S. Knox, and M.I. Liddicoat. 1979. The relationship between inorganic and organic nutrients in sea water. Journal of the Marine Biological Association of the UK 59:239–250. [CrossRef]
17. Carpenter, S.R., W.A. Brock, J.J. Cole, J.F. Kitchell, and M.L. Pace. 2008. Leading indicators of trophic cascades. Ecology Letters 11:128–138.
18. Chavez, F.P., J. Ryan, S.E. Lluch-Cota, and M. Niquen C. 2003. From anchovies to sardines and back: Multidecadal change in the Pacific Ocean. Science 299:217–221. [CrossRef]
19. Chelton, D.B., P.A. Bernal, and J.A. McGowan. 1982. Large-scale interannual physical and biological interaction in the California Current. Journal of Marine Research 40:1,095–1,125.
20. Church, M.J., C. Mahaffey, R.M. Letelier, R. Lukas, J.P. Zehr, and D.M. Karl. 2009. Physical forcing of nitrogen fixation and diazotroph community structure in the North Pacific subtropical gyre. Global Biogeochemical Cycles 23, GB2020. [CrossRef]
21. Cooper, L.H.N. 1938. Phosphate in the English Channel, 1933–1938, with a comparison with earlier years, 1916 and 1923–1932. Journal of the Marine Biological Association of the UK 23:181–195. [CrossRef]
22. Corno, G., D.M. Karl, M.J. Church, R.M. Letelier, R. Lukas, R.R. Bidigare, and M.R. Abbott. 2007. Impact of climate forcing on ecosystem processes in the North Pacific Subtropical Gyre. Journal of Geophysical Research 112, C04021. [CrossRef]
23. Cushing, D.H., and R.R. Dickson. 1976. The biological response in the sea to climatic changes. Advances in Marine Biology 14:1–122. [CrossRef]
24. DeLong, E.F., and D.M. Karl. 2005. Genomic perspectives in microbial oceanography. Nature 437:336–342. [CrossRef]
25. Dickey, T.D. 1991. The emergence of concurrent high-resolution physical and bio-optical measurements in the upper ocean and their applications. Reviews of Geophysics 29(3):383–413. [CrossRef]
26. Dickson, A.G., J.D. Afghan, and G.C. Anderson. 2003. Reference materials for oceanic CO2 analysis: A method for the certification of total alkalinity. Marine Chemistry 80:185–197. [CrossRef]
27. Dinsmore, R.P. 1996. Alpha, Bravo, Charlie…Ocean Weather Ships 1940–1980. Oceanus Fall/Winter:9–10. Available online at: http://www.whoi.edu/oceanus/viewArticle.do?id=2343 (accessed August 5, 2010).
28. Doney, S.C. 1999. Major challenges confronting marine biogeochemical modeling. Global Biogeochemical Cycles 13:705–714. [CrossRef]
29. Doney, S.C., M.R. Abbott, J.J. Cullen, D.M. Karl, and L. Rothstein. 2004. From genes to ecosystems: The ocean’s new frontier. Frontiers in Ecology and the Environment 2:457–466. [CrossRef]
30. Dore, J.E., R.M. Letelier, M.J. Church, R. Lukas, and D.M. Karl. 2008. Summer phytoplankton blooms in the oligotrophic North Pacific Subtropical Gyre: Historical perspective and recent observations. Progress in Oceanography 76:2–38. [CrossRef]
31. Dore, J.E., R. Lukas, D.W. Sadler, M.J. Church, and D.M. Karl. 2009. Physical and biogeochemical modulation of ocean acidification in the central North Pacific. Proceedings of the National Academy of Sciences of the United States of America 106:12,235–12,240. [CrossRef]
32. Duarte, C.M., J. Cebrián, and N. Marbà. 1992. Uncertainty of detecting sea change. Nature 356:190. [CrossRef]
33. Edwards, M., and A.J. Richardson. 2004. Impact of climate change on marine pelagic phenology and trophic mismatch. Nature 430:881–884. [CrossRef]
34. Franklin, J.F., C.S. Bledsoe, and J.T. Callahan. 1990. Contributions of the Long-Term Ecological Research program. BioScience 40:509–523. [CrossRef]
35. Frias-Lopez, J., Y. Shi, G.W. Tyson, M.L. Coleman, S.C. Schuster, S.W. Chisholm, and E.F. DeLong. 2008. Microbial community gene expression in ocean surface waters. Proceedings of the National Academy of Sciences of the United States of America 105:3,805–3,810.
36. Glover, D.M., P.H. Wiebe, C.L. Chandler, and S. Levitus. 2010. IOC contributions to international, interdisciplinary open data sharing. Oceanography 23(3):140–151. [CrossRef]
37. Gordon, D.C. Jr. 1970. Chemical and Biological Observations at Station Gollum, an Oceanic Station Near Hawaii, January 1969 to June 1970. Hawaii Institute of Geophysics Report, HIG-70-22, 44 pp.
38. Hansell, D.A. 2005. Dissolved organic carbon reference material program. Eos, Transactions, American Geophysical Union 86:318. [CrossRef]
39. Harvey, H.W. 1926. Nitrate in the sea. Journal of the Marine Biological Association of the UK 14:71–88. [CrossRef]
40. Harvey, H.W. 1928. Nitrate in the sea. II. Journal of the Marine Biological Association of the UK 15:183–190. [CrossRef]
41. Harvey, H.W. 1934. Measurement of phytoplankton population. Journal of the Marine Biological Association of the UK 19:761–773. [CrossRef]
42. Harvey, H.W. 1942. Production of life in the sea. Biological Review of the Cambridge Philosophical Society 17:221–246. [CrossRef]
43. Harvey, H.W. 1950. On the production of living matter in the sea off Plymouth. Journal of the Marine Biological Association of the UK 29:97–137. [CrossRef]
44. Harvey, H.W. 1955. The Chemistry and Fertility of Sea Waters. University Press, Cambridge, Great Britain, 224 pp.
45. Harvey, H.W., L.H.N. Cooper, M.V. Lebour, and F.S. Russell. 1935. Plankton production and its control. Journal of the Marine Biological Association of the UK 20:407–442. [CrossRef]
46. Haury, L.R., C.L. Fey, and E. Shulenberger. 1994. Surface enrichment of inorganic nutrients in the North Pacific Ocean. Deep-Sea Research 41:1,191–1,205.
47. Hayward, T.L. 1987. The nutrient distribution and primary production in the central North Pacific. Deep-Sea Research 34:1,593–1,627.
48. Hayward, T.L. 1991. Primary production in the North Pacific Central Gyre: A controversy with important implications. Trends in Ecology and Evolution 6:281–284. [CrossRef]
49. Hofmann, E.E., and E. Gross. 2010. IOC contributions to science synthesis. Oceanography 23(3):152–159. [CrossRef]
50. Ives, A.R., and S.R. Carpenter. 2007. Stability and diversity of ecosystems. Science 317:58–62. [CrossRef]
51. Johnson, K.S., S.C. Riser, and D.M. Karl. 2010. Nitrate supply from deep to near-surface waters of the North Pacific subtropical gyre. Nature 465:1,062–1,065.
52. Joint, I., M.B. Jordan, and M.R. Carr. 1997. Is phosphate part of the Russell Cycle? Journal of the Marine Biological Association of the UK 77:625–633. [CrossRef]
53. Jordan, M.B., and I. Joint. 1998. Seasonal variation in nitrate:phosphate ratios in the English Channel 1923–1987. Estuarine and Coastal Shelf Science 46:157–164. [CrossRef]
54. Karl, D.M. 1999. A sea of change: Biogeochemical variability in the North Pacific subtropical gyre. Ecosystems 2:181–214. [CrossRef]
55. Karl, D.M. 2002. Nutrient dynamics in the deep blue sea. Trends in Microbiology 10:410–418. [CrossRef]
56. Karl, D.M. 2007a. Microbial oceanography: Paradigms, processes and promise. Nature Reviews Microbiology 5:759–769. [CrossRef]
57. Karl, D.M. 2007b. The marine phosphorus cycle. Pp. 523–539 in Manual of Environmental Microbiology, 3rd ed. C.J. Hurst et al., eds, American Society of Microbiology.
58. Karl, D.M., and R. Lukas. 1996. The Hawaii Ocean Time-series (HOT) program: Background, rationale and field implementation. Deep-Sea Research Part II 43:129–156. [CrossRef]
59. Karl, D.M., and A.F. Michaels, eds. 1996. Ocean time-series: Results from the Hawaii and Bermuda research programs. Deep-Sea Research Part II 43(2–3).
60. Karl, D.M., and G. Tien. 1992. MAGIC: A sensitive and precise method for measuring dissolved phosphorus in aquatic environments. Limnology and Oceanography 37:105–116. [CrossRef]
61. Karl, D.M., and G. Tien. 1997. Temporal variability in dissolved phosphorus concentrations in the subtropical North Pacific Ocean. Marine Chemistry 56:77–96. [CrossRef]
62. Karl, D.M., and C.D. Winn. 1991. A sea of change: Monitoring the oceans’ carbon cycle. Environmental Science and Technology 25:1,976–1,981.
63. Karl, D.M., R.R. Bidigare, and R.M. Letelier. 2001. Long-term changes in plankton community structure and productivity in the North Pacific Subtropical Gyre: The domain shift hypothesis. Deep-Sea Research Part II 48:1,449–1,470.
64. Karl, D.M., N.R. Bates, S. Emerson, P.J. Harrison, C. Jeandel, O. Llinas, K.-K. Liu, J.-C. Marty, A.F. Michaels, J.C. Miquel, and others. 2003. Temporal studies of biogeochemical processes determined from ocean time-series observations during the JGOFS era. Pp. 239–267 in Ocean Biogeochemistry: The Role of the Ocean Carbon Cycle in Global Change. M.J.R. Fasham, ed., Springer.
65. Keeling, C.D. 1998. Rewards and penalties of monitoring the Earth. Annual Review of Energy and Environment 23:25–82. [CrossRef]
66. Mantua, N.J., S.R. Hare, Y. Zhang, J.M. Wallace, and R.C. Francis. 1997. A Pacific interdecadal climate oscillation with impacts on salmon production. Bulletin of the American Meteorological Society 78:1,069–1,079.
67. Matthews, D.J. 1916. On the amount of phosphoric acid in the sea-water off Plymouth Sound. Journal of the Marine Biological Association of the UK 11:122–130. [CrossRef]
68. Matthews, D.J. 1917. On the amount of phosphoric acid in the sea-water off Plymouth Sound. II. Journal of the Marine Biological Association of the UK 11:251–257. [CrossRef]
69. McGillicuddy, D.J. Jr., B. deYoung, S.C. Doney, P.M. Glibert, D. Stammer, and F.E. Werner. 2010. Models: Tools for synthesis in international oceanographic research programs. Oceanography 23(3):126–139. [CrossRef]
70. McGowan, J.A., and P.W. Walker. 1985. Dominance and diversity maintenance in an oceanic ecosystem. Ecological Monographs 55:103–118. [CrossRef]
71. Michaels, A.F., and A.H. Knap. 1996. Overview of the US JGOFS Bermuda Atlantic Time-series Study and the Hydrostation S program. Deep-Sea Research Part II 43:157–198. [CrossRef]
72. Mills, E.L. 1989. Biological Oceanography: An Early History, 1870–1960. Cornell University Press, Ithaca, New York, 378 pp.
73. Østerhus, S., I. Skjelvan, and T. Gammelsrød. 2009. Weather ship station M in the Norwegian Sea “Polarfront”: The flagship of climate research. IOP Conference Series: Earth and Environmental Science 6:032022.
74. Overland, J.E., D.B. Percival, and H.O. Mofjeld. 2006. Regime shifts and red noise in the North Pacific. Deep-Sea Research Part I 53:582–588. [CrossRef]
75. Pinkerton, M.H., S.J. Lavender, and J. Aiken. 2003. Validation of SeaWiFS ocean color satellite data using a moored databuoy. Journal of Geophysical Research 108(C5), 3133. [CrossRef]
76. Platt, T., W.G. Harrison, M.R. Lewis, W.K.W. Li, S. Sathyendranath, R.E. Smith, and A.F. Vezina. 1989. Biological production of the oceans: The case for a consensus. Marine Ecology Progress Series 52:77–88. [CrossRef]
77. Polovina, J.J., G.T. Mitchum, N.E. Graham, M.P. Craig, E.E. DeMartini, and E.N. Flint. 1994. Physical and biological consequences of a climate event in the central North Pacific. Fisheries Oceanography 3:15–21. [CrossRef]
78. Polovina, J.J., E.A. Howell, and M. Abecassis. 2008. Ocean’s least productive waters are expanding. Geophysical Research Letters 35, L03618. [CrossRef]
79. Poole, H.H., and W.R.G. Atkins. 1937. The penetration into the sea of light of various wave-lengths as measured by emission or rectifier photo-electric cells. Proceedings of the Royal Society of London B 123:151. [CrossRef]
80. Pomeroy, L.R. 1981. Microbial processes in the sea: Diversity in nature and science. Pp. 1–23 in Heterotrophic Activity in the Sea. J.E. Hobbie and P.J.leB. Williams, eds, Plenum Press.
81. Redfield, A.C. 1958. The inadequacy of experiment in marine biology. Pp. 17–26 in Perspectives in Marine Biology. A.A. Buzzati-Traverso, ed., University of California Press.
82. Reid, P.C., J.M. Colebrook, J.B.L. Matthews, J. Aiken, and Continuous Plankton Recorder Team. 2003. The Continuous Plankton Recorder: Concepts and history, from Plankton Indicator to undulating recorders. Progress in Oceanography 58:117–173. [CrossRef]
83. Riser, S.C., and K.S. Johnson. 2008. Net production of oxygen in the subtropical ocean. Nature 451:323–325. [CrossRef]
84. Rodriguez, F., E. Fernandez, R.N. Head, D.S. Harbour, G. Bratbak, M. Heldal, and R.P. Harris. 2000. Temporal variability of viruses, bacteria, phytoplankton and zooplankton in the western English Channel off Plymouth. Journal of the Marine Biological Association of the UK 80:575–586. [CrossRef]
85. Rothstein, L.M., J.J. Cullen, M. Abbott, E. Chassignet, K. Denman, S. Doney, H. Ducklow, K. Fennel, M. Follows, D. Haidvogel, and others. 2006. Modeling ocean ecosystems: The PARADIGM program. Oceanography 19(1):17–45. [pdf]
86. Russell, F.S., A.J. Southward, G.T. Boalch, and E.I. Butler. 1971. Changes in biological conditions in the English Channel off Plymouth during the last half century. Nature 234:468–470. [CrossRef]
87. Saba, V.S., M.A.M. Friedrichs, M.-E. Carr, D. Antoine, R.A. Armstrong, I. Asanuma, O. Aumont, N.R. Bates, M.J. Behrenfeld, V. Bennington, and others. 2010. Challenges of modeling depth-integrated marine primary productivity over multiple decades: A case study at BATS and HOT. Global Biogeochemical Cycles 24. [CrossRef]
88. Sabine, C.L., H. Ducklow, and M. Hood. 2010. International carbon coordination: Roger Revelle’s legacy in the Intergovernmental Oceanographic Commission. Oceanography 23(3):48–61. [CrossRef]
89. Southward, A.J. 1960. On changes of sea temperature in the English Channel. Journal of the Marine Biological Association of the UK 39:449–458. [CrossRef]
90. Southward, A.J. 1974. Changes in the plankton community of the Western English Channel. Nature 249:180–181. [CrossRef]
91. Southward, A.J. 1980. The western English Channel: An inconstant ecosystem? Nature 285:361–366. [CrossRef]
92. Southward, A.J. 1995. The importance of long time-series in understanding the variability of natural systems. Helgolander Meeresuntersuchungen 49:329–333. [CrossRef]
93. Southward, A.J., and E.K. Roberts. 1987. One hundred years of marine research at Plymouth. Journal of the Marine Biological Association of the UK 67:465–506. [CrossRef]
94. Southward, A.J., G.T. Boalch, and L. Maddock. 1988. Fluctuations in the herring and pilchard fisheries of Devon and Cornwall linked to change in climate since the 16th century. Journal of the Marine Biological Association of the UK 68:423–445. [CrossRef]
95. Stommel, H. 1963. Varieties of oceanographic experience. Science 139:572–576. [CrossRef]
96. Strayer, D., J.S. Glitzenstein, C.G. Jones, J. Kolasoi, G.E. Likens, M.J. McDonnell, G.G. Parker, and S.T.A. Pickett. 1986. Long-term ecological studies: An illustrated account of their design, operation, and importance to ecology. Occasional Publication of the Institute of Ecosystem Studies, No. 2. Millbrook, New York.
97. Strayer, D.L., H.A. Ewing, and S. Bigelow. 2003. What kind of spatial and temporal details are required in models of heterogeneous systems? Oikos 102:654–662. [CrossRef]
98. Sverdrup, H.U., M.W. Johnson, and R.H. Fleming. 1946. The Oceans. Prentice-Hall, Englewood Cliffs, NJ, 320 pp.
99. Swanson, F.J., and R.E. Sparks. 1990. Long-term ecological research and the invisible place. BioScience 40:502–508. [CrossRef]
100. Valdés, L., L. Fonseca, and K. Tedesco. 2010. Looking into the future of ocean sciences: An IOC perspective. Oceanography 23(3):160–175. [pdf]
101. Venrick, E.L. 1990. Phytoplankton in an oligotrophic ocean: Species structure and interannual variability. Ecology 71:1,547–1,563.
102. Venrick, E.L., J.A. McGowan, D.R. Cayan, and T.L. Hayward. 1987. Climate and chlorophyll a: Long-term trends in the central North Pacific Ocean. Science 238:70–72. [CrossRef]

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